Combining ultra-high resolution and high-level automation, the Innoscan 1100 AL is perfect for fast, complete imaging.
With three excitation wavelengths, it is ideal for reading cellular microarrays as well as classic three-color microarrays.

“Ideal for reading three-color Microarray scanner Applications”

This combined with a real-time autofocus system and PMT confocal detection, the Innoscan 1100 AL provides high-quality images for detailed microarray analysis.

• Easy Automation: Equipped with easy-to-use image capture software and a 24-slide automatic loader, Innoscan 1100 AL is capable of fully automated scanning of 24 slides at a time.
• The Innoscan 1100 AL can scan any microscope slide with various substrates: cells, tissues, proteins, DNA, glycans, peptides and more. Equipped with three excitation channels, it allows users to have greater multiplexing capabilities, thus allowing the analysis of different samples or markers on the same slide

The Innoscan 1100 AL is the ideal instrument for rapid, automated imaging of entire slides:

• Cellular Micromatrix: Microenvironmental matrices, Peptide/HLA microarrays, Reverse Transmitter Matrices…
• Tissue immunofluorescence
• Three-color microarrays
• High Density Microarray

In the following fields of application:

• Ultrasound of cells and tissues
• Glycomics: glycan arrays
• Proteomics: Peptide Arrays
• Biomarkers and disease stratification
• Food Industry
• Pharmaceutical industry

Advanced Technology

The Innoscan 1100 AL is a confocal scanner equipped with 3 excitation lasers (488, 532 and 635nm) which are coupled with 3 highly sensitive photomultiplier tubes (PMTs) that enable slide imaging. The PMTs are linear across the entire dynamic range (1% to 100%) making it easy for the user to set PMT gain levels for perfect tuning of the fluorescence signal to avoid saturation.

The Innoscan 1100 AL has the highest resolution on the market (up to 0.5 µm/pixel) and uses a real-time autofocus system that adapts to substrate distortion, making the entire reading area completely uniform. Innoscan scanners are renowned for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.

Thanks to the Extended Dynamic Range (XDR) mode, Innoscan scanners have a dynamic range of over 106 and are therefore able to detect the weakest signals while avoiding saturated spots.

Ideal tool for reading high density microarrays

With its new detection system, the Innoscan 910 has the highest resolution and read speed on the market. This simple two-color scanner is the ideal tool for reading current and future high-density microarrays.

Main Features

Featuring ease of use, competitive pricing and superior image quality, the Innoscan 910 is the ideal instrument for scanning the highest density microarrays currently available on the market.

• High Resolution: Innoscan 910 is a high resolution 2-color fluorescence scanner. It is capable of reading microarrays at a very high image quality with a resolution of 1µm/pixel.
• Speed : Able to simultaneously read 2 detection channels in 3.55 minutes (at 10µm/pixel maximum reading area); Innoscan 910 is the fastest scanner on the market with an adjustable scanning speed from 10 to 35 lines/second.
• Reliable and traceable results : With a barcode reader, Innoscan 910 provides accurate control of the scanned images. Innoscan 910 comes with a validation slide and proprietary Mapix software that verifies the scanner’s performance.

Given the size of the images obtained (5.74 GB to read an entire slide at a resolution of 1 µm), Mapix image analysis software was specifically designed to handle large files.

Applications

Innoscan 910 is ideal for reading high-density microarrays currently available on the market:

• High density CGH arrays (6X80K, 4X180K)
• High-density protein array
• Nimblegen HD2 and HD4 slides

In the following fields of application:

• Functional genomics: CNV, genotyping, DNA methylation
• Transcriptomics: Gene Expression, MiRNA
• Proteomics: protein expression, antibody array.

Technology

The Innoscan 910 is a confocal scanner equipped with 2 highly sensitive analog photomultiplier tubes (PMT), inear gain over the range of 0.1 to 100% and is capable of detecting from 0 to 1% gain with a step of 0.01%. This makes it easy for the user to set the PMT gains and adjust the fluorescence signal levels for the 2 colors, managing the saturation level and balancing the 2 channels.

Like the Innoscan 710, the Innoscan 910 uses a real-time autofocus system which has the advantage of making it adaptable to substrate distortion, thus making the entire reading area completely uniform.

Thanks to the XDR (Extended Dynamic Range) mode, Innoscan scanners have a dynamic range greater than 106 and are therefore able to detect the lowest signals while avoiding saturation.

Innoscan scanners are well known for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.