Sanitization ISS Report Hydrogen Peroxide
Specific regulatory scope
Hydrogen peroxide is a biocidal active substance approved under the BPR for disinfectants PT1, PT2, PT2, PT4 and PT5. Based on the data available in the CAR – Competent Authority Report, the active substance is effective against numerous microorganisms (bacteria, yeasts, fungi and viruses). Specifically, with regard to viruses, hydrogen peroxide has been found to be effective against poliovirus and adenovirus. In this case, only the application by vaporization/aerosolization of the active substance is considered.
Technical-scientific evaluation
The mechanism of action of hydrogen peroxide is linked to its oxidizing properties and the denaturation of essential components of microorganisms. In fact, the antimicrobial activity arises from the formation of powerful oxidants, such as 15-hydroxyl radicals and oxygen singlets. These reactive species cause irreversible damage to cellular components and DNA.
Depending on the application method, it can have multiple uses. There is a typical decontamination process based on hydrogen peroxide in the form of plasma gas, with which a predetermined rate of hydrogen peroxide is vaporized and injected into a decontamination chamber. The aim is to promote the formation of a thin film of hydrogen peroxide on exposed surfaces as quickly as possible. Once the required amount of hydrogen peroxide has been dispensed, the aeration phase takes place; where the hydrogen peroxide vapor is catalytically converted into oxygen and water. For surface/room disinfection, hydrogen peroxide can be applied by aerosol or steam.
Diffusion in the Environment
Diffusion by aerosol, with equipment capable of producing particles in the order of 0.3-0.5 µm, allows for uniform diffusion in the environment. Responsible for the biocidal action of the product are the highly oxidizing hydroxyl radicals OH-. The application of vaporized hydrogen peroxide has proven effective not only on a large number of microorganisms but also for the treatment of hospital environments that had hosted patients affected by the Lassa and Ebola viruses (56,57). Hydrogen peroxide decomposes rapidly into water and oxygen in various environmental districts, such as surface water, soil and air. Furthermore, it decomposes already in the sewage before reaching the sewage system, with a low environmental impact.
Finally, with regard to its hazardous nature, hydrogen peroxide is classified in a harmonised way according to CLP31 as: oxidising liquid of category 1 [Ox. Liq. 1 – “may cause fire or explosion (strong oxidiser)]”; corrosive to the skin of category 1 (Skin. Corr. 1A – “causes severe skin burns and serious eye damage”) and harmful if swallowed and if inhaled of category 4 (Acute Tox. 4 – “harmful if swallowed” and “harmful if inhaled”).
Usage
Given the classification of the active ingredient, as well as the method of application, the use of vaporized/aerosolized hydrogen peroxide is restricted to professional operators only. For treatments, the appropriate precautions must therefore be observed (DL.vo 81/2008) and it is also necessary to respect the times for access to the premises and the decay times.
Phileas
Phileas machines are Automatic Equipment for the Aerial Disinfection of Surfaces by uniform diffusion of Stabilized Hydrogen Peroxide H2O2. Phileas technology atomizes hydrogen peroxide into small particles, spreading them into the environment with a nebulizer.
The particles can then spread throughout the environment, sanitizing the air and surfaces. Once its action is over, hydrogen peroxide degrades into water and oxygen, substances that do not cause harm to the environment or people.
Phileas Genius: a concentration of technology
Treated volumes: from 0.2 to 5 m³;
Minimum dimensions with optimal results;
Specially designed footrest makes Genius rotatable and height-adjustable;
Long energy autonomy thanks to its NiMh battery;
Flow rate adapted for very small spaces.
Phileas 25: robustness without the weight
Treated volumes: 1 to 40 m³;
The programming cycles allow for optimised disinfection in complete autonomy;
Portable machine with integrated ergonomic handles;
Integrated liquid container;
Dual power supply: main power or battery (option);
The product’s flow rate and size are suitable for treating small volumes.
Phileas 75: volume and mobility
Treated volumes: from 10 to 180 m³;
With a high treatment capacity, it offers an excellent compromise between autonomy and mobility;
Easy mobility thanks to the wheels and retractable handle;
Large diffusion capacity thanks to its 2-litre container;
Specific indicator of liquid usage;
Suitable for medium-sized rooms and volumes.
Phileas 250: Power and precision
Treated volumes: from 50 to 800 m³;
Specially designed for harsh environments, such as industrial facilities
and laboratories with large volumes;
Diffusion power thanks to double heads and high flow rate;
Maneuverability and mobility combined with robustness;
Liquid usage indicator and large capacity tank;
Developed for large volume and multi-room uses.
